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The results suggest that PCs augment high glucose-induced apoptosis in pancreatic -cells by increasing glucose uptake under high glucose conditions, potentially via a mechanism that downregulates Gck and promotes Bax protein translocation and oligomerization at the mitochondrial membrane

Diffusion tensor imaging studies in migraine without aura have described thalamic microstructural changes between attacks in particular increased fractional anisotropy that varies with time since the last attack and appears to normalise during the attack itself [30] and correlated structuralfunctional alterations of the thalamo-cortical network [31]

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