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APE1 inhibitor APX3330(E3330) could promote the treatment of colorectal cancer tumors by inhibiting the REDOX function of APE1 in combination with 5-FU

In some instances, a hyaluronidase is a bovine hyaluronidase (e.g., bovine testicular hyaluronidase, Amphadase (Amphastar Pharmaceuticals), Hydase (PrimaPharm, Inc)

4-Hydroxynonenal is involved in the signaling of cell proliferation and apoptosis, as well as regulating gene expression in different cell types (Yang et al., 2001