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Accompanying symptoms of this condition include local pain, swelling of the lower leg or entire limb, skin redness, as well as Homan's sign, where there is calf pain during dorsiflexion of the foot

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The 1 mg/day arm produced 2.6 kg weight loss over 12 weeks versus 0.8 kg placebo

This is particularly powerful for patients who are overweight and experiencing severe trouble losing weight with other interventions