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Structural and functional changes of the BBB in PD Evidence for increased BBB permeability in human postmortem tissues Early attempts to study BBB permeability in PD did not detect overt disruptions, although the presence of mononuclear cells infiltrating the substantia nigra and the striatum suggested neuroinflammation, a major BBB disruptor [115,116,117]

Eremin KO, et al

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