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Reproduced from Kaneto et al (2021), an open source publication ( Indications: a FIRST LINE drug in the treatment of type II diabetes ( except when contraindicated - see below) Metformin has been in use for over 50 yrs, and remains the most commonly prescribed oral hypoglycemic (DeFronzo & Goodman, 1995

Breast milk and the importance of chrononutrition

Because probiotics stay in the colon only temporarily, regular consumption is necessary to maintain their populations in the colon

The published literature spans animal and in vitro models across gastrointestinal, soft-tissue, neurological, vascular, and bone-research endpoints, but it does not establish human therapeutic use