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Identify gaps in the literature and ongoing research directions Key gaps include a lack of large, controlled clinical trials, unclear optimal dosing and delivery for reproductive targets, limited long-term safety data for systemic use, and few mechanistic human studies linking molecular changes to fertility outcomes

Human data for meniscus tears specifically is limited to case reports and patient testimonials

Sekhar RV, McKay SV, Patel SG, Guthikonda AP, Reddy VT, Balasubramanyam A, et al

[3] Glucocorticoids (like prednisolone) are among the most common causes of secondary osteoporosis, and they work partly by suppressing GH/IGF-1 signaling