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In T cells of SLE patients, mTOR activation triggers ROS production, while SIRT2 concurrently upregulates IL-17A expression in these cells by modulating the mTOR complex 1 (mTORC1)/HIF-1/RORt signaling pathway, thereby contributing to the pathogenesis of SLE (101, 155)

Hypoglycemia is one of the first manifestations of metabolic reprogramming during the early phases of liver regeneration after PHx, which is likely attributable to a marked reduction in hepatic glycogen stores and gluconeogenic capacity in the metabolic stress response

PubMed / International Journal of Molecular Sciences

It must be indicated that in earlier studies 10,11,17 the concentration of N-Hcy-Lys was less than 0.1 nmol/mL and in most cases could not be reliably determined in healthy individuals