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Consortia must also include at least one funded patient partner, brought in through a PAO or another organised patient group, and must secure access to a qualified multinational Clinical Trial Management Organisation (CTMO)

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This is not unheard of, as drugs like pioglitazone and acipimox both reduce metabolic complications without treating obesity at all

Practical Considerations Titration may be needed: Starting lower and building up could minimize GI side effects