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During the pathogenesis of OA, JUN directly binds to the promoter of NCOA4 and initializes its transcription, increasing ferritinophagy degradation, leading to ferroptosis and extracellular matrix degradation in chondrocytes

During ejaculation, a typical fertile male releases between 40 million to 300 million sperm cells, but only a small fraction survive the journey through the cervix, uterus, and fallopian tubes

15 nM BG-ASO over 25 nM control ASO (dark blue), 15 nM BG-ASO and 10 nM control ASO over 25 nM control ASO (light blue), 15 nM BG-ASO and 35 nM control ASO over 100 nM control ASO (orange), and 15 nM BG-ASO and 85 nM control ASO over 100 nM control ASO (red)

The analysis revealed a rapid disruption of the bacterial membrane