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Rosiglitazone promotes fatty acyl CoA accumulation and excessive glycogen storage in livers of mice without adiponectin

Spermatidic giant cells were observed in monkeys after 6-month treatment at 30 mg/kg/day in addition to vacuolation of seminiferous tubular epithelium

10.1371/journal.pone.0158632 [DOI] [PMC free article] [PubMed] [Google Scholar] Kim, S

By repressing cardiac peroxisome proliferator-activated receptor-, miR-199a facilitates a metabolic shift from a predominant reliance on fatty acid utilization toward an increased reliance on glucose metabolism, which leads to lethal heart failure (36)