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S5) shows that GDH closed conformer has the largest LRC, roughly about ~ 1.8 times bigger than the LRC in the open form, with lowest total independent degree of freedoms (DOF)

Final results of a phase I study of the histone deacetylase inhibitor vorinostat (suberoyanilide hydroxamic acid, SAHA), in patients with leukemia and myelodysplastic syndrome