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Jiang W, Hiscox S, Matsumoto K, Nakamura T

3 ), which results in the rupture of the outer mitochondrial membrane and the release of intermembrane proteins, including endonuclease G and apoptosis-inducing factor (AIF)

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Japanese industry tracker Nikkei says that the system will have a "3-D joystick" and a "force feedback mechanism that will let players feel the collisions of a game character." Also promised are "significant improvements" in wireless communications, though the screen will likely be smaller than the DSi XL's