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However, in the pivotal Phase IIb trial, it failed to demonstrate statistically significant weight loss compared to placebo at the primary endpoint, leading the developer (Metabolic Pharmaceuticals Ltd.) to terminate the commercial program

[7] The scientists also commented, Very surprisingly, Ipamorelin did not [appear to] release ACTH or cortisol in levels significantly different from those observed following GHRH stimulation

The discomfort is typically minimal and brief

Our team will provide you with aftercare instructions and discuss any possible side effects, such as mild redness or tenderness at the injection site, which typically resolve quickly on their own