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Studies have suggested that increased susceptibility to KBD in selenium-deficient populations might result from a reduced antioxidant protection associated with polymorphisms in GPX genes (60, 61), but polymorphisms in other genes have also been implicated (62)

Notably, the percentage of basophils ( Figure 3D ) showed a significant group effect (p G = 0.019) in addition to the time effect

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Nevertheless, the utilization of metformin during pregnancy is typically determined following a collaborative evaluation of the potential risks and benefits by obstetricians and reproductive endocrinologists in current clinical practice