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There are few things more frustrating than living your life plagued by digestive symptoms such as bloating, constipation, cramping and irregularity

To explore this idea, we bred the MMTV-PyMT transgenic mouse strain (which spontaneously develops breast tumours) 26 with an uninduced Gclc f/f Rosa26 creERT2 mouse 27 in which the rate-limiting step in GSH synthesis, the glutamatecysteine ligase catalytic subunit (GCLC), can be knocked out throughout the body after induction with tamoxifen

BMC Syst Biol 2018;12:89

If endogenous glutamine production does not meet the bodys needs, the potential benefits of exogenous glutamine supplementation should be considered