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They are based on the principle of heating, which is the key difference, and at the same time, other harmful properties resulting from combustion are also eliminated

In addition to a background level of mutations in the sixty-first codon identical to those observed in spontaneous hepatocellular neoplasms, additional point mutations were documented in codons 12 or 117 of the H-ras proto-oncogene in addition to the activation of K-ras and N-ras oncogenes in chemically treated mice that had an unequivocal increase in hepatocellular tumors

For example, the elevated levels of TNF- after 20 weeks smoking was back to baseline levels after 8 weeks smoking cessation in the broncho-alveolar lavage fluid of mice 33 and similarly 30 days smoking cessation resulted in a significant reduction in TNF- in humans 28

Although the presence of heavy metals in e-cigarettes is lower than that of tobacco cigarettes, it can still be a potentially dangerous amount of metal to inhale when used regularly