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Preclinical studies in rodent models have evaluated outcomes such as fat oxidation, body-weight change patterns, and metabolic markers tied to fat breakdown and storage

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25 Castelli MC, Friedman K, Sherry J et al (2011) Comparing the efficacy and tolerability of a new daily oral vitamin B12 formulation and intermittent intramuscular vitamin B12 in normalizing low cobalamin levels: a randomized, open-label, parallel-group study