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10.1562/2004-09-18-RA-320 139 KleinE

Unlike systemic immunotherapies that are limited by toxicity and off-target effects, injectable or implantable hydrogels can provide localized, sustained, and precisely dosed delivery of immune modulators [61]

which helps reduce wrinkles in the skin, are very well understood scientifically

A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/beta-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans