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Effect of low-dose selenium on thyroid autoimmunity and thyroid function in uk pregnant women with mild-to-Moderate iodine deficiency

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HFD inhibits the transcription of key antioxidant genes by triggering NRF2 translocation into obese mouse Tregs nucleus, causing a rapid decline in HO-1 expression in Tregs, leading to enhanced oxidative stress and possible ferroptosis, and causing an intensification of obesity and inflammatory responses (156) ( Figure 3 )

However, by increasing glutamate and excessive activation of glutamate receptors, it could be a critical strike to dopaminergic neurons in PD patients