In addition, Cox2, the marker of lipid peroxidation during ferroptosis, was significantly reduced after DMF treatment
ROS are directly or indirectly associated with cytokine storm induction in SARS-CoV-2 infection, and ROS can activate NF-B and NLRP3 inflammasomes, thereby leading to the production of inflammatory cytokines and the development of acute respiratory distress syndrome and multiple organ dysfunction 62,63,64
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