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Control Clin

Standard Dose Escalation Timeline The recommended cagrilintide dosage schedule involves gradual titration over 16-20 weeks : Week 1-4 : 0.3 mg weekly Week 5-8 : 0.6 mg weekly Week 9-12 : 1.2 mg weekly Week 13-16 : 1.8 mg weekly Week 17+ : 2.4 mg weekly (maintenance dose) This stepped approach allows the body to adapt to cagrilintide's effects on gastric emptying and appetite regulation, significantly reducing nausea and vomiting incidence

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However, this increase was still lower than the control group, which increased its cortisol hormone to 3.450ng/ml, although it was also not significant (p=0.064) (Table 1)