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Description

doi: 10.1080/17474124.2019.1685381

ferroptosis promotes cell sensitivity to apoptosis, apoptosis can be transformed into ferroptosis under certain conditions, autophagy promotes ferroptosis (184), and ferroptosis regulators interact with cuprotosis

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In this paper, we consider as outcomes of interest the [GSH]/[GSSG] ratio and the model outputs for the concentration of NADPH, ROS and G6P at time points for which calibration and validation data measurements are available (PN12, PN13, PN15, PN17, PN28)