l carnitine or berberine and supplement Berberine 1000 mg Supplement Divine Bounty Acetyl L-Carnitine &

Jul 2014;12(7):1090-1100.e1092

These results indicate that the DEC-containing serum significantly inhibits melanin production and deposition, thereby attenuating skin pigmentation through the downregulation of MITF and TYR expression

Brain fatigue is associated with prolonged mental effort, stress, or neurological conditions, including stroke, multiple sclerosis (MS), Parkinsons disease, dementia, brain tumors, neuroinflammation (encephalitis, meningitis), head injuries, exhaustion syndrome, and neuropsychiatric conditions: ADHD/ADD, autism, cerebral hypoxia, endocrine diseases that affect the brain, and myalgic encephalopathy [5,6]

The studies described above further establish mTOR activity to be a crucial factor in the gut-immune-brain axis playing a key role in the regulation of ASD-associated behavior