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Description

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Phase I and phase II trials are also underway to assess the safety and pharmacokinetics of small molecule inhibitors of LOXL2, such as GB2064 (NCT04679870) and PXS-5382 A (NCT04183517)

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In some embodiments, the otic formulation or composition comprises about 0.09% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof

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