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An alternative strategy could involve the understanding of the molecular mechanisms underlying the known risk factors and to correct them, when possible, as a prevention/treatment of the disease

Intracellular levels of pyrimidine influence the replication and transcription of both nuclear and mitochondrial genomes

Preclinical and cell culture research has examined exogenous glutathione for its capacity to replenish intracellular GSH pools under oxidative stress conditions, modulating Nrf2/ARE pathway activity and mitochondrial redox balance