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These are striking results because this is the first randomized study to show that a BCMA-targeted bispecific therapy can outperform a lenalidomide-based approach in high-risk smoldering myeloma, said Omar Nadeem, MD, medical director of the Center of Early Detection and Interception of Blood Cancers

In models testing antioxidant capacity, using partially degraded material produces false negatives

Sample preparation (B) In an alternate protocol, the frozen liver tissue was directly lysed by probe sonication (2 10 pulse, 40% power output) in 4 M urea/DPBS and briefly cleared of debris by centrifugation (5000 g , 5 min, 4 C)

It also reduced enteric serotonin release while suppressing intestinal motility