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Additionally, catalpol inhibits the activation of the nucleotide-binding oligomerization domain containing 2 (NOD2)/NF-B/mitogen-activated protein kinase (MAPK) signaling pathway, playing an anti-inflammatory and protective role in mouse chondrocytes

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Dysfunction of cystinosin results in the intralysosomal accumulation of the disulfide cystine, which crystallizes in some tissues and damages many parenchymal organs