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Safety concerns for IV cosmetic use: Regulatory advisories and reports of serious adverse events, without long-term safety data or standardized dosing, drive strong criticism of IV GSH for skin lightening

However, its expression has been demonstrated in different tissues such as the blood-brain barrier (BBB), choroid plexus, lung, heart, intestine, kidney, placenta, and testis [127]

Preclinical studies have demonstrated that the sequential application of photodynamic therapy and radiotherapy significantly improves therapeutic outcomes for triple-negative breast cancer, highlighting the potential of combined therapies [133]

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