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From earlier work focused on muscular dystrophy conducted with former Penn Dental Medicine faculty member Elizabeth Barton, now at the University of Florida, the researchers believed that a particular form of IGF, a precursor of the protein that includes a separate component known as an e-peptide, was likely to stimulate regeneration better than mature IGF-1 that lacked the peptide

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Exploring such diagnoses is important, as genetic malfunction may also be manifesting in less visible systems e.g., impact on the cardiovascular, autonomic, gastro-intestinal and urogenital systems

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