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A common polymorphism in HIBCH influences methylmalonic acid concentrations in blood independently of cobalamin Am J Hum Genet 2016;98:869-82

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Compared to GLP-1 Agonists: Weight management peptides like semaglutide and tirzepatide have demonstrated weight loss efficacy superior to AOD-9604 in clinical trials, but they also have distinct side effect profiles

Furthermore, most monitoring guidelines, including both the MHRA in the UK [9] and the ADA [33], suggest the need for periodic vitamin B 12 monitoring but do not provide a monitoring frequency, which probably leads to lack of monitoring